I have always liked the skill symbolic strike. I tried to use signets that were actually effective on the main build, but the variant focuses more on pure damage, so most of the signets are only minimally effective. Obviously, having another player maintain Great Dwarf Weapon on you would be beneficial. See below for dervish variant.
<pvxbig> [build prof=W/A str=8+1 swo=12+1+1 dead=10][Crippling Slash][Gash][Symbolic Strike][Flail][Signet of Infection][Signet of Deadly Corruption][Dolyak Signet][Sunspear Rebirth Signet][/build] </pvxbig>
Use Crippling Slash --> Gash --> Signet of Infection to cause conditions for Signet of Deadly Corruption during SS downtime. Use an Infuriating Heat ranger to spam SS.
<pvxbig> [build prof=W/R str=12+1 swo=12+1+1 tactic=3+1][Symbolic Strike][antidote signet][dolyak signet][signet of strength][tryptophan signet][healing signet][sunspear rebirth signet][battle rage][/build] </pvxbig>